{"id":8757,"date":"2017-04-21T23:04:53","date_gmt":"2017-04-21T21:04:53","guid":{"rendered":"http:\/\/box5654.temp.domains\/~akplustr\/attaer\/?p=8757"},"modified":"2017-04-21T23:04:53","modified_gmt":"2017-04-21T21:04:53","slug":"%d8%a7%d9%84%d8%ac%d9%86%d9%80%d9%8a%d9%86-%d9%88%d9%86%d8%b8%d9%80%d9%80%d8%a7%d9%85-%d8%a7%d9%84%d9%85%d9%86%d9%80%d8%a7%d8%b9%d9%80%d8%a9-%d8%a3%d9%8a%d9%80%d8%a9-%d8%ad%d9%85%d8%a7%d9%8a%d9%80","status":"publish","type":"post","link":"https:\/\/attaer.com\/?p=8757","title":{"rendered":"\u0627\u0644\u062c\u0646\u0640\u064a\u0646 \u0648\u0646\u0638\u0640\u0640\u0627\u0645 \u0627\u0644\u0645\u0646\u0640\u0627\u0639\u0640\u0629 \u0623\u064a\u0640\u0629 \u062d\u0645\u0627\u064a\u0640\u0629 \u0644\u0647 \u0623\u062b\u0646\u0640\u0627\u0621 \u0627\u0644\u062d\u0645\u0644\u061f"},"content":{"rendered":"<p><strong>\u0627\u0644\u0637\u0627\u0626\u0631 &#8211; \u0644\u0628\u0646\u0627\u0646:<\/strong><\/p>\n<p><a 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\u0627\u0646\u062e\u0641\u0627\u0636 \u0645\u0646\u0627\u0639\u0629 \u0627\u0644\u0623\u0645 \u0627\u0644\u062d\u0627\u0645\u0644 \u062e\u0644\u0627\u0644 \u0641\u062a\u0631\u0629 \u0627\u0644\u062d\u0645\u0644\u060c \u0648\u0642\u062f \u0638\u0647\u0631 \u0639\u062f\u0645 \u0635\u0648\u0627\u0628\u064a\u0629 \u0647\u0630\u0647 \u0627\u0644\u0641\u0631\u0636\u064a\u0629 \u0643\u0648\u0646 \u0627\u0644\u0625\u064a\u062c\u0627\u0628\u0627\u062a \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 \u0644\u062f\u0649 \u0627\u0644\u0623\u0645 \u0627\u0644\u062d\u0627\u0645\u0644 \u0643\u0627\u0646\u062a \u063a\u064a\u0631 \u0642\u0627\u0635\u0631\u0629 \u0648\u0645\u062a\u0648\u0641\u0631\u0629.<\/p>\n<p><strong>\u0627\u0644\u0641\u0631\u0636\u064a\u0629 \u0627\u0644\u062b\u0627\u0644\u062b\u0629<\/strong> \u0627\u062f\u0639\u062a \u0628\u0623\u0646 \u0631\u062d\u0645 \u0627\u0644\u0623\u0645 \u0642\u062f \u064a\u0643\u0648\u0646 \u0628\u0642\u0639\u0629 \u0645\u0645\u064a\u0632\u0629 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\u0627\u0644\u062a\u062d\u0645\u0644 \u0647\u0645 \u0645\u0646 \u0646\u0627\u062d\u064a\u0629\u060c \u0627\u0644\u062c\u0630\u0639\u0629 \u0627\u0644\u0627\u063a\u062a\u0630\u0627\u0626\u064a\u0629 \u0627\u0644\u0645\u0631\u0643\u0628\u0629 \u0645\u0646 \u0637\u0628\u0642\u0629 \u062e\u0627\u0631\u062c\u064a\u0629 (syncitiotrophoblaste) \u0648\u0637\u0628\u0642\u0629 \u062f\u0627\u062e\u0644\u064a\u0629 (cytotrophoblaste) \u0648\u0645\u0646 \u0646\u0627\u062d\u064a\u0629 \u0623\u062e\u0631\u0649 \u062c\u062f\u0627\u0631 \u0627\u0644\u0631\u062d\u0645 \u0627\u0644\u0633\u0627\u0642\u0637.<\/p>\n<p><strong>\u0622\u0644\u064a\u0627\u062a \u0627\u0644\u062a\u062d\u0645\u0651\u0644<\/strong><\/p>\n<p>\u0625\u0646 \u062a\u062d\u0645\u0644 \u0627\u0644\u0623\u0645 \u0644\u062c\u0646\u064a\u0646\u0647\u0627 \u0645\u0646 \u0627\u0644\u0646\u0627\u062d\u064a\u0629 \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629\u060c \u0646\u0627\u062a\u062c \u0639\u0646 \u0638\u0648\u0627\u0647\u0631 \u0639\u062f\u0629 \u062a\u062a\u0643\u0627\u0645\u0644 \u0648\u062a\u062a\u0643\u0627\u0645\u0646 \u0641\u064a\u0645\u0627 \u0628\u064a\u0646\u0647\u0627 \u0648\u062a\u062d\u062f\u064a\u062f\u0627\u064b\u060c \u062a\u062e\u0635\u0635\u064a\u0629 \u0627\u0644\u0645\u064f\u062c\u0645\u0651\u0639 \u0627\u0644\u0631\u0626\u064a\u0633\u064a \u0644\u062a\u0648\u0627\u0641\u0642 \u0623\u0646\u0633\u062c\u0629 \u0627\u0644\u062c\u0633\u0645 \u0648\u0627\u0644\u0645\u0639\u0631\u0648\u0641 \u0628\u0645\u062c\u0645\u0639 (CMH) \u0627\u0644\u0645\u0648\u062c\u0648\u062f \u0639\u0644\u0649 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0646\u064a\u0646\u064a\u0629 \u0644\u0644\u062c\u0630\u0639\u0629 \u0627\u0644\u0627\u063a\u062a\u0630\u0627\u0626\u064a\u0629 \u0627\u0644\u0645\u0634\u0627\u0631 \u0625\u0644\u064a\u0647\u0627 \u0622\u0646\u0641\u0627\u064b\u060c \u062b\u0645 \u062e\u0627\u0635\u064a\u0629 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0642\u0627\u062a\u0644\u0629 (NK) \u0627\u0644\u0645\u062a\u0648\u0627\u062c\u062f\u0629 \u0641\u064a \u0627\u0644\u063a\u0634\u0627\u0621 \u0627\u0644\u0645\u0634\u064a\u0645\u064a \u0623\u0648 \u0627\u0644\u0643\u0648\u0631\u064a\u0648\u0646\u060c \u0648\u0645\u064a\u0632\u0627\u0646 th1\/th2 \u0648\u0643\u0630\u0644\u0643 \u062f\u0648\u0631 \u0627\u0644\u0633\u064a\u062a\u0648\u0643\u064a\u0646\u0627\u062a \u0627\u0644\u062a\u064a \u062a\u0641\u0631\u0632\u0647\u0627 \u0627\u0644\u0643\u0631\u064a\u0627\u062a \u0627\u0644\u0644\u0645\u0641\u0627\u0648\u064a\u0629 \u0644\u062c\u062f\u0627\u0631 \u0627\u0644\u0631\u062d\u0645.<\/p>\n<p><strong>\u062f\u0648\u0631 \u0646\u0638\u0627\u0645 CMH<\/strong><\/p>\n<p>\u064a\u0646\u062d\u0635\u0631 \u062f\u0648\u0631 \u0645\u064f\u062c\u0645\u0651\u0639 \u062a\u0648\u0627\u0641\u0642 \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0648\u0627\u0644\u0645\u0633\u0645\u0649 \u0623\u064a\u0636\u0627\u064b (HLA) \u0623\u0648 (Human Leucocyte Antigens)\u060c \u0641\u064a \u0645\u062c\u0627\u0644 \u0627\u0644\u062a\u0639\u0631\u0641 \u0639\u0644\u0649 \u0627\u0644\u0630\u0627\u062a \u0648\u0627\u0644\u0644\u0627\u0630\u0627\u062a\u060c \u0648\u0647\u0648 \u0639\u0628\u0627\u0631\u0629 \u0639\u0646 \u0645\u062c\u0645\u0648\u0639\u0629 \u0645\u0646 \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0627\u0644\u0645\u0648\u062c\u0648\u062f\u0629 \u0648\u0627\u0644\u0645\u062a\u0645\u0631\u0643\u0632\u0629 \u0639\u0644\u0649 \u0627\u0644\u0630\u0631\u0627\u0639 \u0627\u0644\u0623\u0642\u0635\u0631 \u0644\u0644\u0635\u0628\u063a\u064a \u0627\u0644\u0633\u0627\u062f\u0633\u060c \u0648\u0627\u0644\u062a\u064a \u062a\u062d\u062f\u062f \u0643\u064a\u0641\u064a\u0629 \u0635\u0646\u0639 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u0627\u0644\u0645\u0635\u0646\u0641\u0629 \u0644\u0639\u062f\u0629 \u0641\u0626\u0627\u062a. \u0647\u0630\u0627 \u0627\u0644\u0646\u0638\u0627\u0645 \u0647\u0648 \u0645\u062a\u0639\u062f\u062f \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0648\u0627\u0644\u0622\u0644\u064a\u0644\u0627\u062a (all\u00e8les)\u060c \u0645\u0627 \u064a\u062d\u062a\u0645 \u062a\u0646\u0648\u0639 \u0643\u0628\u064a\u0631 \u0641\u064a \u0625\u0645\u0643\u0627\u0646\u064a\u0627\u062a \u0627\u0644\u062e\u0644\u0637 \u0628\u064a\u0646 \u0627\u0644\u0623\u0641\u0631\u0627\u062f\u060c \u0643\u0645\u0627 \u0648\u064a\u0634\u0645\u0644 \u0644\u062f\u0649 \u0627\u0644\u0628\u0634\u0631 \u0635\u0646\u0641\u064a\u0646 \u0645\u062e\u062a\u0644\u0641\u064a\u0646:<\/p>\n<p>\u0646\u0638\u0627\u0645 CMH \u0635\u0646\u0641 \u0623\u0648\u0644 \u0648\u0641\u064a\u0647 \u062b\u0644\u0627\u062b \u0641\u0626\u0627\u062a \u0645\u062a\u0639\u062f\u062f\u0629 \u0627\u0644\u0622\u0644\u064a\u0644\u0627\u062a \u0647\u064a (HLA-A)\u060c (HLA-B) \u0648(HLA-C) \u0648\u064a\u064f\u062a\u0631\u062c\u0645 \u0639\u0644\u0649 \u0634\u0643\u0644 \u062c\u0632\u064a\u0626\u0627\u062a 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\u062c\u0632\u064a\u0626\u0627\u062a \u0623\u0646\u0638\u0645\u0629 (HLA-A) \u0648(HLA-B) \u0648(HLA-C)\u060c \u0628\u0627\u0633\u062a\u062b\u0646\u0627\u0621 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062d\u0627\u0645\u0644\u0629 \u0644\u062c\u0632\u064a\u0626\u0627\u062a \u0646\u0638\u0627\u0645 (HLA-G)\u060c \u0627\u0644\u062a\u064a \u062a\u0628\u0642\u0649 \u0628\u0645\u0646\u0623\u0649 \u0639\u0646 \u0630\u0627\u0643 \u0627\u0644\u062a\u062f\u0645\u064a\u0631 \u0627\u0644\u062e\u0644\u0648\u064a. \u062a\u0645\u062b\u0644 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0642\u0627\u062a\u0644\u0629 \u0646\u0633\u0628\u0629 70 \u0628\u0627\u0644\u0645\u0626\u0629 \u0645\u0646 \u0627\u0644\u0643\u0631\u064a\u0627\u062a \u0627\u0644\u0644\u0645\u0641\u0627\u0648\u064a\u0629 \u0644\u062c\u062f\u0627\u0631 \u0627\u0644\u0631\u062d\u0645\u060c \u0648\u064a\u0632\u062f\u0627\u062f \u0639\u062f\u062f\u0647\u0627 \u0628\u0639\u064a\u062f 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\u0627\u0644\u0645\u062a\u0644\u0642\u064a KIR \u0627\u0644\u0645\u0646\u062a\u0645\u064a \u0644\u0639\u0627\u0626\u0644\u0629 \u0645\u0636\u0627\u062f\u0627\u062a \u0623\u062c\u0633\u0627\u0645\u060c \u064a\u0644\u062a\u0635\u0642 \u0639\u0644\u0649 \u062c\u0632\u064a\u0626\u0627\u062a \u0646\u0638\u0627\u0645 (HLA) \u0635\u0646\u0641 \u0623\u0648\u0644 \u0645\u0643\u0628\u062d\u0627\u064b \u0627\u0644\u0648\u0638\u0627\u0626\u0641 \u0627\u0644\u0627\u0646\u062d\u0644\u0627\u0644\u064a\u0629 \u0644\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0642\u0627\u062a\u0644\u0629. \u0648\u0628\u0627\u0644\u0645\u0642\u0627\u0628\u0644 \u064a\u0639\u0645\u0644 \u0627\u0644\u0645\u062a\u0644\u0642\u064a KAR \u0639\u0644\u0649 \u062e\u0633\u0641 \u062d\u0628\u064a\u0628\u0627\u062a\u0647\u0627. \u0648\u0645\u0646 \u062c\u0647\u062a\u0647\u0627 \u062a\u0633\u062a\u0637\u064a\u0639 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u062a\u0631\u062c\u0645\u0629 \u0644\u0646\u0638\u0627\u0645 (HLA-G)\u060c \u0627\u0644\u0627\u0644\u062a\u0635\u0627\u0642 \u0628\u0645\u062a\u0644\u0642\u064a (KIR) \u0627\u0644\u0645\u062a\u0645\u0631\u0643\u0632 \u0639\u0644\u0649 \u0633\u0637\u062d \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0642\u0627\u062a\u0644\u0629 \u0648\u0627\u0644\u0643\u0631\u064a\u0627\u062a \u0627\u0644\u0644\u0645\u0641\u0627\u0648\u064a\u0629 TCD8\u060c \u0645\u0627 \u064a\u062d\u0648\u0644 \u062f\u0648\u0646 \u0636\u0631\u0631 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0642\u0627\u062a\u0644\u0629 \u0648\u062e\u0644\u0627\u064a\u0627 (CD8) \u0627\u0644\u0623\u0645\u0631 \u0627\u0644\u0630\u064a \u064a\u0633\u0627\u0647\u0645 \u0628\u0646\u062c\u0627\u062d \u0639\u0645\u0644\u064a\u0629 \u062a\u062d\u0645\u0644 \u0627\u0644\u062c\u0646\u064a\u0646 \u0627\u0644\u062a\u064a \u062a\u062a\u0639\u0632\u0651\u0632 \u0623\u064a\u0636\u0627\u064b \u0625\u062b\u0631 \u0639\u0645\u0644\u064a\u0629 \u0627\u0644\u0645\u0648\u062a \u0627\u0644\u0645\u0628\u0631\u0645\u062c \u0644\u062e\u0644\u0627\u064a\u0627 CD8 (apoptose). \u0648\u0627\u0644\u062c\u0640\u062f\u064a\u0631 \u0628\u0627\u0644\u0630\u0643\u0631 \u0623\u0646 \u062f\u0648\u0631 \u0646\u0638\u0627\u0645 (HLA-G) \u0648\u0636\u0644\u0648\u0639\u0647 \u0641\u064a \u0627\u0633\u062a\u062a\u0628\u0627\u0628 \u0627\u0644\u0642\u062f\u0631\u0629 \u0639\u0644\u0649 \u062a\u062d\u0645\u0644 \u0627\u0644\u062c\u0646\u064a\u0646\u060c \u064a\u0645\u0643\u0646 \u0623\u0646 \u064a\u0642\u0627\u0631\u0646 \u0628\u0645\u0627 \u064a\u062d\u0635\u0644 \u0644\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0633\u0631\u0637\u0627\u0646\u064a\u0629 \u0644\u0645\u0631\u0636 \u0642\u062a\u0627\u0645\u064a\u0646\u064a (m\u00e9lanome) \u0627\u0644\u062a\u064a \u062a\u064f\u062a\u0631\u062c\u0645 \u0646\u0638\u0627\u0645 (HLA-G)\u060c \u0641\u062a\u0645\u0646\u0639 \u062a\u0627\u0644\u064a\u0627\u064b \u0627\u0644\u062a\u062f\u0645\u064a\u0631 \u0627\u0644\u0635\u0627\u062f\u0631 \u0639\u0646 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0642\u0627\u062a\u0644\u0629\u060c \u0645\u0627 \u064a\u0634\u0643\u0644 \u0622\u0644\u064a\u0629 \u0625\u0641\u0644\u0627\u062a \u0645\u0646 \u0628\u0639\u0636 \u0627\u0644\u0633\u0631\u0637\u0627\u0646\u0627\u062a \u0644\u0646\u0627\u062d\u064a\u0629 \u0627\u0644\u0631\u0642\u0627\u0628\u0629 \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629.<\/p>\n<p><strong>\u062f\u0648\u0631 \u0627\u0644\u0633\u064a\u062a\u0648\u0643\u064a\u0646\u0627\u062a:<\/strong><\/p>\n<p><strong>\u0645\u064a\u0632\u0627\u0646 <\/strong><strong>th<\/strong><strong>1\/<\/strong><strong>th<\/strong><strong>2<\/strong><\/p>\n<p>\u062a\u064f\u0635\u0646\u0651\u0641 \u0627\u0644\u0643\u0631\u064a\u0627\u062a \u0627\u0644\u0644\u0645\u0641\u0627\u0648\u064a\u0629 (T) \u0641\u064a \u0627\u0644\u062c\u0633\u0645 \u0637\u0628\u0642\u0627\u064b \u0644\u0644\u0633\u064a\u062a\u0648\u0643\u064a\u0646\u0627\u062a \u0627\u0644\u062a\u064a \u062a\u0646\u062a\u062c\u0647\u0627\u060c \u0625\u0644\u0649 \u0643\u0631\u064a\u0627\u062a \u0644\u0645\u0641\u0627\u0648\u064a\u0629 (th1) \u0648(th2). \u0627\u0644\u0635\u0646\u0641 \u0627\u0644\u0623\u0648\u0644 (th1) \u064a\u0646\u062a\u062c \u0633\u064a\u062a\u0648\u0643\u064a\u0646\u0627\u062a \u0645\u0646 \u0646\u0648\u0639 (IL-2) \u0648(IFNg) \u0648(INF\u00e1)\u060c \u0627\u0644\u0645\u0646\u0634\u0637\u0629 \u0644\u0644\u0645\u0644\u062a\u0647\u0645\u0627\u062a (macrophages) \u0648\u0644\u0644\u0625\u064a\u062c\u0627\u0628\u0627\u062a \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 \u0627\u0644\u062e\u0644\u0648\u064a\u0629 \u0627\u0644\u0645\u0639\u0646\u064a\u0629 \u0641\u064a \u0638\u0648\u0627\u0647\u0631 \u0631\u0641\u0636 \u0627\u0644\u0632\u0631\u0639 \u063a\u064a\u0631 \u0627\u0644\u0645\u062a\u0648\u0627\u0641\u0642. \u0648\u0628\u0627\u0644\u0645\u0642\u0627\u0628\u0644 \u062a\u064f\u0631\u0643\u0628 \u0627\u0644\u0643\u0631\u064a\u0627\u062a (th2)\u060c \u0633\u064a\u062a\u0648\u0643\u064a\u0646\u0627\u062a \u0645\u0636\u0627\u062f\u0629 \u0644\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u0627\u062a \u0645\u062b\u0644: IL-4 \u0648IL-5 \u0648IL-6\u060c \u0627\u0644\u0645\u0633\u0627\u0647\u0645\u0629 \u0641\u064a \u0627\u0644\u062c\u0648\u0627\u0628 \u0627\u0644\u0645\u0646\u0627\u0639\u064a \u0627\u0644\u062e\u0644\u0637\u064a \u0623\u064a \u0628\u0648\u0627\u0633\u0637\u0629 \u0645\u0636\u0627\u062f\u0627\u062a \u0627\u0644\u0623\u062c\u0633\u0640\u0640\u0627\u0645. \u0648\u0623\u064a\u0640\u0640\u0636\u0640\u0627\u064b \u062a\u0646\u062a\u062c \u0633\u064a\u062a\u0648\u0643\u064a\u0646\u0640\u0627\u062a IL-10 \u0648TGF\u00df \u0627\u0644\u0639\u0627\u062f\u0645\u0629 \u0644\u0644\u0645\u0646\u0627\u0639\u0629 \u0648\u0627\u0644\u0645\u0639\u0646\u064a\u0629 \u0641\u064a \u0638\u0648\u0627\u0647\u0631 \u062a\u0646\u0638\u064a\u0645 \u0627\u0644\u062c\u0648\u0627\u0628 \u0627\u0644\u0645\u0646\u0627\u0639\u064a \u0648\u0641\u064a \u0627\u0644\u0642\u062f\u0631\u0629 \u0639\u0644\u0649 \u062a\u062d\u0645\u0644 \u0627\u0644\u062c\u0646\u064a\u0646 \u0648\u0641\u064a \u0647\u0630\u0647 \u0627\u0644\u0635\u062f\u062f\u060c \u062a\u0628\u064a\u0646 \u0644\u0627\u062d\u0642\u0627\u064b\u060c \u062e\u0644\u0627\u0644 \u0641\u062a\u0631\u0629 \u0627\u0644\u062d\u0645\u0644 \u0648\u062c\u0648\u062f \u0647\u064a\u0645\u0646\u0629 \u0644\u0643\u0631\u064a\u0627\u062a (th2) \u0627\u0644\u0645\u0645\u064a\u0632\u0629 \u0628\u0625\u0646\u062a\u0627\u062c \u0645\u0636\u0637\u0631\u062f \u0644\u0644\u0633\u064a\u062a\u0648\u0643\u064a\u0646\u0627\u062a (th2) \u064a\u0642\u0627\u0628\u0644\u0647\u0627 \u0639\u0645\u0644\u064a\u0629 \u0643\u0628\u062d \u0644\u0625\u0646\u062a\u0627\u062c \u0633\u064a\u062a\u0648\u0643\u064a\u0646\u0627\u062a (th1).<\/p>\n<p>\u0641\u064a \u0639\u0644\u0645 \u0627\u0644\u0623\u0645\u0631\u0627\u0636\u060c \u062b\u0645\u0629 \u062d\u062c\u062c \u0639\u062f\u0651\u0629\u060c \u062f\u0627\u0639\u0645\u0629 \u0644\u062f\u0648\u0631 \u0627\u0644\u0645\u064a\u0632\u0627\u0646 \u0627\u0644\u0642\u0627\u0626\u0645 \u0628\u064a\u0646 th1\/th2 \u0641\u064a \u0627\u0644\u0642\u062f\u0631\u0629 \u0639\u0644\u0649 \u062a\u062d\u0645\u0644 \u0627\u0644\u062c\u0646\u064a\u0646. \u0648\u0647\u0646\u0627\u0643 \u0628\u0639\u0636 \u062d\u0627\u0644\u0627\u062a \u0625\u062c\u0647\u0627\u0636 \u0639\u0627\u0626\u062f\u0629 \u0644\u062e\u0644\u0644 \u0641\u064a \u0630\u0627\u0643 \u0627\u0644\u0645\u064a\u0632\u0627\u0646.<\/p>\n<p><strong>\u062f\u0648\u0631 \u0627\u0644\u0643\u0631\u064a\u0627\u062a \u0627\u0644\u0644\u0645\u0641\u0627\u0648\u064a\u0629 \u0627\u0644\u0645\u0646\u0638\u0651\u0650\u0645\u0629<\/strong><\/p>\n<p>\u062a\u0624\u062b\u0631 \u0627\u0644\u0643\u0631\u064a\u0627\u062a \u0627\u0644\u0644\u0645\u0641\u0627\u0648\u064a\u0629 (T) \u0627\u0644\u0645\u0646\u0638\u0651\u0650\u0645\u0629 (treg) \u0639\u0644\u0649 \u0638\u0648\u0627\u0647\u0631 \u0627\u0644\u0642\u062f\u0631\u0629 \u0639\u0644\u0649 \u062a\u062d\u0645\u0644 \u0627\u0644\u062c\u0646\u064a\u0646\u060c \u0648\u0630\u0644\u0643 \u0628\u0627\u0644\u062d\u062f\u0651 \u0645\u0646 \u0627\u0644\u0625\u064a\u062c\u0627\u0628\u0627\u062a \u0627\u0644\u0646\u0648\u0639\u064a\u0629 \u0639\u0644\u0649 \u0627\u0644\u0623\u0646\u062a\u064a\u062c\u064a\u0646. \u0625\u0646 \u062a\u062d\u0645\u0644 \u0627\u0644\u062c\u0646\u064a\u0646\u060c \u064a\u062a\u0645 \u0645\u0646 \u0627\u0644\u0646\u0627\u062d\u064a\u0629 \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 \u0628\u0648\u0627\u0633\u0637\u0629 \u062a\u0644\u0643 \u0627\u0644\u0643\u0631\u064a\u0627\u062a \u0627\u0644\u0644\u0645\u0641\u0627\u0648\u064a\u0629 \u0627\u0644\u0645\u0646\u0638\u0645\u0629\u060c \u0627\u0644\u062a\u064a \u062a\u062c\u0646\u0628 \u0627\u0644\u0625\u062c\u0647\u0627\u0636 \u0628\u062e\u0644\u0642\u0647\u0627 \u0628\u064a\u0626\u0629 \u0645\u0635\u063a\u0631\u0629 \u0645\u0644\u0627\u0626\u0645\u0629 \u0644\u0644\u0642\u062f\u0631\u0629 \u0639\u0644\u0649 \u0627\u0644\u062a\u062d\u0645\u0644\u060c \u0648\u0645\u062a\u0645\u064a\u0632\u0629 \u0628\u0646\u0633\u0628 \u0645\u0631\u062a\u0641\u0639\u0629 \u0644\u0639\u0627\u0645\u0644 TGF\u00df \u0648\u0639\u0627\u0645\u0644 LIF \u0627\u0644\u0645\u0639\u0646\u0649 \u0645\u0639 \u0645\u062a\u0644\u0642\u064a\u0647 \u0628\u0627\u0646\u063a\u0631\u0627\u0632 \u0643\u064a\u0633 \u0627\u0644\u062c\u0631\u062b\u0648\u0645\u0629. \u0644\u0642\u062f \u0623\u062b\u0628\u062a\u062a \u062f\u0631\u0627\u0633\u0627\u062a \u062d\u062f\u064a\u062b\u0629 \u0627\u0631\u062a\u0641\u0627\u0639\u0627\u064b \u0645\u0644\u062d\u0648\u0638\u0627\u064b \u0641\u064a \u0646\u0633\u0628\u0629 \u0627\u0644\u0643\u0631\u064a\u0627\u062a \u0627\u0644\u0645\u0646\u0638\u0645\u0629 (treg) \u0641\u064a \u0627\u0644\u062f\u0645\u060c \u062e\u0644\u0627\u0644 \u0627\u0644\u0641\u0635\u0644 \u0627\u0644\u0623\u0648\u0644 \u0645\u0646 \u0627\u0644\u062d\u0645\u0644\u060c \u062b\u0645 \u062b\u0628\u0627\u062a\u0627\u064b \u062e\u0644\u0627\u0644 \u0627\u0644\u0641\u0635\u0644 \u0627\u0644\u062b\u0627\u0646\u064a \u064a\u0644\u064a\u0647 \u0641\u064a\u0645\u0627 \u0628\u0639\u062f \u0647\u0628\u0648\u0637\u0627\u064b \u0644\u0647\u0627.<\/p>\n<p><strong>\u062f\u0648\u0631 \u0622\u0644\u064a\u0627\u062a \u0648\u062c\u0632\u064a\u0626\u0627\u062a \u0623\u062e\u0631\u0649<\/strong><\/p>\n<p>\u062b\u0645\u0629 \u0622\u0644\u064a\u0627\u062a \u0623\u062e\u0631\u0649 \u0645\u0639\u0646\u064a\u0629 \u0641\u064a \u0627\u0644\u0642\u062f\u0631\u0629 \u0639\u0644\u0649 \u062a\u062d\u0645\u0644 \u0627\u0644\u062c\u0646\u064a\u0646\u060c \u064a\u0646\u0628\u063a\u064a \u0627\u0644\u062a\u0637\u0631\u0642 \u0625\u0644\u064a\u0647\u0627\u060c \u0643\u062f\u0648\u0631 \u0627\u0644\u0645\u062a\u0644\u0642\u064a\u0627\u062a (r\u00e9cepteurs) \u0641\u064a \u0639\u0645\u0644\u064a\u0629 \u0627\u0644\u0645\u0648\u062a \u0627\u0644\u062e\u0644\u0648\u064a \u0627\u0644\u0645\u0628\u0631\u0645\u062c \u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0623\u0645 \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 \u0627\u0644\u0645\u0646\u0634\u064e\u0637\u0629. \u0641\u0641\u064a \u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u062b\u0627\u0646\u064a\u0629 \u0644\u0644\u062f\u0648\u0631\u0629 \u0627\u0644\u0634\u0647\u0631\u064a\u0629\u060c \u064a\u0646\u062a\u062c \u062c\u062f\u0627\u0631 \u0627\u0644\u0631\u062d\u0645 \u062c\u0632\u064a\u0626\u0629 (LIF)\u060c \u0648\u062e\u0644\u0627\u0644 \u0627\u0646\u063a\u0631\u0627\u0632 \u0643\u064a\u0633 \u0627\u0644\u062c\u0631\u062b\u0648\u0645\u0629 \u0641\u064a \u0627\u0644\u062c\u062f\u0627\u0631\u060c \u062a\u064f\u0638\u0647\u0631 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u0629 \u0627\u0644\u0627\u063a\u062a\u0630\u0627\u0626\u064a\u0629 \u0623\u0648 \u0627\u0644\u0637\u0628\u0642\u0629 \u0627\u0644\u0628\u062f\u0627\u0626\u064a\u0629\u060c \u0645\u062a\u0644\u0642\u064a \u062e\u0627\u0635 \u0644\u062c\u0632\u064a\u0626\u0629 (LIF) \u064a\u0633\u0645\u0649 (LIF-R) \u0627\u0644\u0630\u064a \u0628\u0639\u062f \u0627\u0644\u062a\u0635\u0627\u0642\u0647 \u0628\u062a\u0644\u0643 \u0627\u0644\u062c\u0632\u064a\u0626\u0629 \u064a\u0624\u0645\u0646 \u0628\u064a\u0626\u0629 \u0645\u0635\u063a\u0651\u0631\u0629 \u0645\u0624\u0627\u062a\u064a\u0629 \u0644\u0644\u0642\u062f\u0631\u0629 \u0639\u0644\u0649 \u0627\u0644\u062a\u062d\u0645\u0644.<\/p>\n<p>\u0622\u0644\u064a\u0629 \u0623\u062e\u0631\u0649 \u064a\u062a\u0648\u062c\u0628 \u0630\u0643\u0631\u0647\u0627 \u0623\u064a\u0636\u0627\u064b\u060c \u062a\u062a\u0645\u062b\u0644 \u0628\u0627\u062d\u062a\u0648\u0627\u0621 \u0627\u0644\u062f\u0645 \u0639\u0644\u0649 \u0639\u0646\u0635\u0631 \u064a\u0633\u0645\u0649 \u0627\u0644\u0645\u0643\u0645\u0644 (compl\u00e9ment)\u060c 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\u0627\u0644\u0642\u0648\u0644 \u0628\u0623\u0646 \u0627\u0644\u0642\u062f\u0631\u0629 \u0639\u0644\u0649 \u062a\u062d\u0645\u0644 \u0627\u0644\u0623\u0645 \u0644\u062c\u0646\u064a\u0646\u0647\u0627 \u062a\u0639\u0648\u062f \u0644\u0639\u0648\u0627\u0645\u0644 \u0639\u062f\u0629\u060c \u062a\u062a\u062f\u062e\u0644 \u0623\u062b\u0646\u0627\u0621 \u0627\u0646\u063a\u0631\u0627\u0632 \u0627\u0644\u062c\u0646\u064a\u0646 \u0641\u064a \u062c\u062f\u0627\u0631 \u0627\u0644\u0631\u062d\u0645 \u0648\u062a\u062a\u0644\u062e\u0635 \u0628\u0627\u0644\u062a\u0627\u0644\u064a:<\/p>\n<p>\u0625\u0646 \u0627\u0644\u062c\u0630\u0639\u0629 \u0627\u0644\u0627\u063a\u062a\u0630\u0627\u0626\u064a\u0629 (trophoblaste) \u0623\u0648 \u0645\u0627 \u064a\u0633\u0645\u0649 \u0628\u0627\u0644\u0637\u0628\u0642\u0629 \u0627\u0644\u0628\u062f\u0627\u0626\u064a\u0629\u060c \u0644\u0627 \u062a\u0638\u0647\u0631 \u0645\u062c\u0645\u0639\u0627\u062a (HLA-A) \u0635\u0646\u0641 \u0623\u0648\u0644\u060c 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